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2025 San Francisco 49ers Season Win Total Picks

by Robert Ferringo - 8/8/2025

San Francisco 49ers season win total picks Brock Purdy

Last year my 8-Unit NFL Futures Play was on San Francisco 49ers to go ‘under’ their 11.5 Las Vegas season win total. In my writeup, I observed that, “Funny thing about championship windows. They normally don't close quietly; they slam shut.”

And last year San Francisco’s window to win a Super Bowl title slammed shut.

I predicted it all. The injuries. The statistical regressions. The overwhelming schedule. The lack of focus on regular season games. The negative karma.

San Francisco’s 6-11 collapse may have been a shock to the general public. But I saw the bad moon rising. I saw the trouble on the way.

Heading into 2025, San Francisco is currently a trendy pick for a bounce back season and their season win total is currently a hefty 10.5.

Is this a football betting market in denial? Or are the same signs that pointed toward a San Francisco disappointment last summer conspiring in favor of the Niners this season?

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SAN FRANCISCO 49ERS 2025 OFFENSE

The 49ers moved the ball with ease last year, finishing No. 4 in total offense and No. 4 in passing yards. They finished just No. 14 in scoring offense, though, in part because they couldn’t stop turning the ball over (27 giveaways).

Brock Purdy contributed 12 of those turnovers via interception. But he apparently played well enough and showed enough leadership to warrant a major contract extension this offseason. It’s Purdy’s offense now. And he will have to perform.

Deebo Samuel is gone (and probably injured himself on the way out the door). That leaves Brandon Aiyuk, who is coming back from an ACL and MCL tear, and second-year wideout Ricky Pearsall, who is coming back from being shot, as the top two wideouts for the Niners.

The Niners are also hoping for a healthy season out of 37-year-old left tackle Trent Williams. He is the fulcrum of an offensive line that doesn’t boast any other Pro Bowl talent.

Finally, the season went off the rails last year when they finally lost Christian McCaffrey. McCaffrey, who has had three other seasons in his career cut short due to injury, was never healthy last year. He missed the first eight games, struggled through four more, and then was shut down for the year while rumors swirled that his career may be over.

By all accounts, McCaffrey is healthy and happy heading into training camp.

SAN FRANCISCO 49ERS 2025 SCHEDULE

Sun, Sep 7        @ Seattle Seahawks                4:05 p.m.

Sun, Sep 14     @ New Orleans Saints             1:00 p.m.

Sun, Sep 21     vs Arizona Cardinals               4:25 p.m.

Sun, Sep 28     vs Jacksonville Jaguars           4:05 p.m.

Thu, Oct 2        @ Los Angeles Rams               8:15 p.m.

Sun, Oct 12      @ Tampa Bay Buccaneers    1:00 p.m.

Sun, Oct 19      vs Atlanta Falcons                    8:20 p.m.

Sun, Oct 26      @ Houston Texans                   1:00 p.m.

Sun, Nov 2       @ New York Giants                  1:00 p.m.

Sun, Nov 9       vs Los Angeles Rams               4:25 p.m.

Sun, Nov 16     @ Arizona Cardinals               4:05 p.m.

Mon, Nov 24   vs Carolina Panthers               8:15 p.m.

Sun, Nov 30     @ Cleveland Browns               1:00 p.m.

Sun, Dec 7        BYE

Sun, Dec 14     vs Tennessee Titans                4:25 p.m.

Mon, Dec 22    @ Indianapolis Colts               8:15 p.m.

Sun, Dec 28     vs Chicago Bears                       8:20 p.m.

Jan 3 or 4         vs Seattle Seahawks               TBD

SAN FRANCISCO 49ERS 2025 SEASON PICKS AND PREDICTIONS

Absolutely everything is pointing up for the Niners this season. Mainly because everything that seemingly could have gone wrong last year, did.

San Francisco went 1-6 in close games last year. They were -10 in turnover differential and -1.4 against their Pythagorean win expectation. There was the excessive number of starts lost to injury. And there was their excessive yards per point numbers on both offense and defense.

Throw in the fact that San Francisco came up a full six games short of their season win total last season and the 49ers qualify as a Triple Pickle Team for me.

I don’t think that San Francisco is nearly as powerful as they were just two years ago. I don’t see the Niners as a true Super Bowl threat and I still think they are going through a modified rebuild.

The Niners don’t need to be a great team to get to 11 wins, though. (Just ask the Chargers last year.) And the fact is that whatever weaknesses they have they are still better than teams like the Panthers, Browns, Titans, Saints, and Bears. As long as San Francisco can manufacture a 3-3 split in their division games I think they will have just enough to get past this number and back into the playoffs.

Take the ‘over’.

Robert Ferringo has posted seven of 10 winning football seasons, including last year thanks to an astounding +10,830 three-month run. Robert banked nearly +40,000 in profit between 2010-2019 for a 10-year average profit of nearly +4,000. He has earned 11 of 16 overall winning years and 69 of 114 winning months while also going 23-9 with his football futures rated 5.0+ and earning 16 of 19 winning Super Bowls. He is a member of the Football Writers Association of America and he is set for another amazing football season. SIGN UP HERE TODAY AND TAKE ADVANTAGE OF OUR 3-FOR-1 FOOTBALL SPECIALS!

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