MLB Picks: Parlays, Expert Predictions, Best Bets and Player Props.

Cleveland Guardians vs Detroit Tigers Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/16/2025

The Cleveland Guardians are on the docket to take on the Detroit Tigers at Comerica Park on Wednesday, September 17, 2025. That matchup occurs at 6:40 PM EST at Comerica Park in Detroit, MI. This matchup report includes betting lines and our pick of the day for this game.

Toronto Blue Jays vs Tampa Bay Rays Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/16/2025

The Toronto Blue Jays are scheduled to take on the Tampa Bay Rays at George M. Steinbrenner Field on Wednesday, September 17, 2025. That matchup will take place at 7:05 PM EST at George M. Steinbrenner Field in Tampa, FL. This matchup report includes betting lines and our pick of the day for this game.

Los Angeles Angels vs Milwaukee Brewers Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/16/2025

The Los Angeles Angels are on the docket to meet the Milwaukee Brewers at American Family Field on Wednesday, September 17, 2025. That meeting is scheduled to begin at 7:40 PM EST at American Family Field in Milwaukee, WI. This matchup report has Vegas lines and an expert MLB pick for your daily winner.

San Francisco Giants vs Arizona Diamondbacks Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Parlay's Pundit - 9/16/2025

The San Francisco Giants are on the docket to meet the Arizona Diamondbacks at Chase Field on Wednesday, September 17, 2025. That contest is scheduled to be shown at 3:40 PM EST at Chase Field in Phoenix, AZ. This report has odds and your MLB predictions for todays game against the spread.

Sacramento Athletics vs Boston Red Sox Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/16/2025

The Sacramento Athletics are on the docket to play the Boston Red Sox at Fenway Park on Wednesday, September 17, 2025. That matchup can be streamed at 6:45 PM EST at Fenway Park in Boston, MA. We have included an expert pick and parlay for todays game against the spread.

Miami Marlins vs Colorado Rockies Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/16/2025

The Miami Marlins are on the docket to play the Colorado Rockies at Coors Field on Wednesday, September 17, 2025. That contest occurs at 8:40 PM EST at Coors Field in Denver, CO. This matchup report includes odds, betting trends and a free pick against the spread.

Seattle Mariners vs Kansas City Royals Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/16/2025

The Seattle Mariners are on the docket to go head to head with the Kansas City Royals at Kauffman Stadium on Wednesday, September 17, 2025. That game occurs at 7:40 PM EST at Kauffman Stadium in Kansas City, MO. This report includes betting odds and our expert MLB picks for todays game.

Philadelphia Phillies vs Los Angeles Dodgers Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/16/2025

The Philadelphia Phillies are set to play the Los Angeles Dodgers at Dodger Stadium on Wednesday, September 17, 2025. That contest can be viewed at 10:10 PM EST at Dodger Stadium in Los Angeles, CA. This game report has an MLB pick, betting odds, and trends for tonights key matchup.

Atlanta Braves vs Washington Nationals Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/16/2025

The Atlanta Braves are on the docket to take on the Washington Nationals at Nationals Park on Wednesday, September 17, 2025. That baseball game can be caught at 4:05 PM EST at Nationals Park in Washington, D.C.. This matchup report includes odds, betting trends and a free pick against the spread.

Texas Rangers vs Houston Astros Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Tony Sink - 9/16/2025

The Texas Rangers are set to go head to head with the Houston Astros at Daikin Park on Wednesday, September 17, 2025. That matchup is scheduled to start at 8:10 PM EST at Daikin Park in Houston, TX. This games report has current odds, betting trends, and free picks against the spread.

Cincinnati Reds vs St. Louis Cardinals Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/16/2025

The Cincinnati Reds are set to play the St. Louis Cardinals at Busch Stadium on Wednesday, September 17, 2025. That contest is set to start at 1:15 PM EST at Busch Stadium in St. Louis, MO. This Matchup report has your MLB pick of the day as well as MLB odds for the game.

Chicago Cubs vs Pittsburgh Pirates Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/16/2025

The Chicago Cubs are set to meet the Pittsburgh Pirates at PNC Park on Wednesday, September 17, 2025. That baseball game will be streamed at 12:35 PM EST at PNC Park in Pittsburgh, PA. This report includes betting odds and our expert MLB picks for todays game.

New York Yankees vs Minnesota Twins Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Guy Bruhn - 9/16/2025

The New York Yankees are scheduled to play the Minnesota Twins at Target Field on Wednesday, September 17, 2025. That matchup is set to begin at 7:40 PM EST at Target Field in Minneapolis, MN. We have included an expert pick and prediction for todays game against the spread.

Baltimore Orioles vs Chicago White Sox Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/16/2025

The Baltimore Orioles are on the docket to take on the Chicago White Sox at Rate Field on Wednesday, September 17, 2025. That contest takes place at 2:10 PM EST at Rate Field in Chicago, IL. This Matchup report includes Vegas odds and a free baseball pick for tonight.

San Diego Padres vs New York Mets Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
by Josh Schonwald - 9/16/2025

The San Diego Padres are scheduled to meet the New York Mets at Citi Field on Wednesday, September 17, 2025. That contest can be watched at 7:10 PM EST at Citi Field in Queens, NY. We have included an expert pick for todays game against the spread.