NFL Picks: Parlays, Best Bets, Player Props, and Expert Predictions Against the Spread.

Denver Broncos vs Los Angeles Chargers Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Guy Bruhn - 9/16/2025

SoFi Stadium is the location where the Los Angeles Chargers (2-0) will try to beat the Denver Broncos (1-1) on Sunday. Los Angeles opens this game as 2.5-point favorites from Vegas oddsmakers. The total is 46. This matchup report includes Vegas odds and a free NFL pick for tonight.

Detroit Lions vs Baltimore Ravens Prediction, 9/22/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025

The Detroit Lions (1-1) are on their way to M&T Bank Stadium on Monday where they will try to defeat the Baltimore Ravens (1-1). Baltimore is 5.5-point favorites. The total comes in at 51.5. This matchup report includes odds, betting predictions and a free pick against the spread.

New York Giants vs Dallas Cowboys Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Josh Schonwald - 9/9/2025

The Dallas Cowboys (0-1) host the New York Giants (0-1) at AT&T Stadium on Sunday. Dallas is 6-point favorites from oddsmakers. The total is set at 44.5. This matchup report includes football betting lines and our pick of the day for this game.

Carolina Panthers vs Arizona Cardinals Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Josh Schonwald - 9/9/2025

The Arizona Cardinals (1-0) will try to beat the Carolina Panthers (0-1) at State Farm Stadium on Sunday. Carolina is 6.5-point underdogs from oddsmakers. The betting total comes in at 44.5. This matchup report includes odds, NFL betting predictions and a free pick against the spread.

Chicago Bears vs Detroit Lions Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Parlays Pundit - 9/9/2025

The Detroit Lions (0-1) are welcoming the Chicago Bears (0-1) at Ford Field on Sunday. Chicago opens this game as 6-point underdogs from Vegas oddsmakers. The over-under is 47.5. We have included an expert NFL pick and parlay for todays game against the spread.

Los Angeles Rams vs Tennessee Titans Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Guy Bruhn - 9/9/2025

The Tennessee Titans (0-1) will take on the Los Angeles Rams (1-0) at Nissan Stadium on Sunday. Tennessee opens this contest as 5.5-point dogs from Vegas oddsmakers. The over-under is 42. This matchup report includes Vegas odds and a free NFL prediction for tonight.

Jacksonville Jaguars vs Cincinnati Bengals Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Guy Bruhn - 9/9/2025

The Cincinnati Bengals (1-0) will compete against the Jacksonville Jaguars (1-0) at Paycor Stadium on Sunday. Cincinnati opens this game as 3.5-point favorites from Vegas oddsmakers. The total is set at 49.5. This report includes betting predictions and our expert NFL picks for todays game.

Buffalo Bills vs New York Jets Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Guy Bruhn - 9/9/2025

The New York Jets (0-1) host the Buffalo Bills (1-0) at MetLife Stadium on Sunday. Buffalo opens this game as 6.5-point favorites from Vegas oddsmakers. The over-under is 46. This matchup report has your NFL football pick of the day as well as NFL football odds for the game.

Atlanta Falcons vs Minnesota Vikings Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Guy Bruhn - 9/9/2025

U.S. Bank Stadium is where the Minnesota Vikings (1-0) will try to beat the Atlanta Falcons (0-1) on Sunday. Minnesota is 4.5-point favorites from oddsmakers. The total is set at 45. This matchup report includes betting lines and our NFL pick of the day for this game.

Tampa Bay Buccaneers vs Houston Texans Prediction, 9/15/2025 NFL Picks, Best Bets & Odds Week 2
by Josh Schonwald - 9/9/2025

The Houston Texans (0-1) will try to beat the Tampa Bay Buccaneers (1-0) at NRG Stadium on Monday. Tampa Bay opens this matchup as 2.5-point dogs. The total is set at 42.5. This matchup report includes Vegas odds and a free NFL pick for tonight.

Denver Broncos vs Indianapolis Colts Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Guy Bruhn - 9/9/2025

The Denver Broncos (1-0) are on their way to Lucas Oil Stadium on Sunday where they will attempt to beat the Indianapolis Colts (1-0). Denver is 2.5-point favorites from oddsmakers. The total has been set at 42. This matchup report includes Vegas odds and a free NFL pick for tonight.

New England Patriots vs Miami Dolphins Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Josh Schonwald - 9/9/2025

The Miami Dolphins (0-1) will try to beat the New England Patriots (0-1) at Hard Rock Stadium on Sunday. Miami opens this game as 1.5-point favorites from Vegas oddsmakers. The total is set at 44. This games report has current odds, betting predictions, and free picks against the spread.

Los Angeles Chargers vs Las Vegas Raiders Prediction, 9/15/2025 NFL Picks, Best Bets & Odds Week 2
by Tony Sink - 9/9/2025

The Los Angeles Chargers (1-0) are headed to Allegiant Stadium on Monday where they will go up against the Las Vegas Raiders (1-0). Los Angeles opens this game as 3.5-point favorites from oddsmakers. The over-under is 47. This matchup report includes odds, betting predictions and a free pick against the spread.

Philadelphia Eagles vs Kansas City Chiefs Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Tony Sink - 9/9/2025

The Kansas City Chiefs (0-1) will try to defeat the Philadelphia Eagles (1-0) at GEHA Field at Arrowhead Stadium on Sunday. Philadelphia opens this matchup as 1-point favorites. The total is set at 47. This report includes betting odds and our expert football picks for todays game.

Seattle Seahawks vs Pittsburgh Steelers Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Josh Schonwald - 9/9/2025

Acrisure Stadium is the location where the Pittsburgh Steelers (1-0) will meet the Seattle Seahawks (0-1) on Sunday. Pittsburgh opens this matchup as 3-point favorites from oddsmakers. The over-under is 40. This report has odds and your NFL football predictions for todays game against the spread.

San Francisco 49ers vs New Orleans Saints Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Tony Sink - 9/9/2025

Caesars Superdome is the location where the New Orleans Saints (0-1) will meet the San Francisco 49ers (1-0) on Sunday. New Orleans is 4.5-point underdogs from oddsmakers. The over-under is 42.5. This matchup report has Vegas lines and an expert NFL football pick for your daily winner.

Washington Commanders vs Green Bay Packers Prediction, 9/11/2025 NFL Picks, Best Bets & Odds Week 2
by Tony Sink - 9/9/2025

The Green Bay Packers (1-0) host the Washington Commanders (1-0) at Lambeau Field on Thursday. Green Bay opens this game as 3.5-point favorites from Vegas oddsmakers. The betting total comes in at 48. This matchup report includes NFL odds, predictions, and a free pick against the spread.