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Detroit Lions vs Chicago Bears Prediction, 1/4/2026 NFL Picks, Best Bets & Odds Week 18
by Josh Schonwald - 1/2/2026

Soldier Field is the site where the Chicago Bears (11-5) will try to defeat the Detroit Lions (8-8) on Sunday. Chicago opens as 3-point favorites from oddsmakers. The total is set at 50.5. This matchup report includes football betting lines and our pick of the day for this game. Read More >>

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Detroit Lions vs Minnesota Vikings Prediction, 12/25/2025 NFL Picks, Best Bets & Odds Week 16
by Guy Bruhn - 12/24/2025

U.S. Bank Stadium is the location where the Minnesota Vikings (7-8) will take on the Detroit Lions (8-7) on Thursday. Minnesota opens as 7.5-point underdogs from oddsmakers. The over-under has been set at 43. This report includes betting predictions and our expert NFL picks for todays game. Read More >>

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Pittsburgh Steelers vs Detroit Lions Prediction, 12/21/2025 NFL Picks, Best Bets & Odds Week 16
by Tony Sink - 12/18/2025

The Pittsburgh Steelers (8-6) are en route to Ford Field on Sunday where they will try to beat the Detroit Lions (8-6). Pittsburgh opens this matchup as 7-point dogs from Vegas oddsmakers. The over-under is set at 52. This report includes betting odds and our expert football picks for todays game. Read More >>

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Detroit Lions vs Los Angeles Rams Prediction, 12/14/2025 NFL Picks, Best Bets & Odds Week 15
by Guy Bruhn - 12/11/2025

The Detroit Lions (8-5) are headed to SoFi Stadium on Sunday where they will compete against the Los Angeles Rams (10-3). Detroit opens as 5.5-point underdogs from Vegas oddsmakers. The total is set at 55.5. This matchup report includes Vegas odds and a free NFL pick for tonight. Read More >>

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Dallas Cowboys vs Detroit Lions Prediction, 12/4/2025 NFL Picks, Best Bets & Odds Week 14
by Tony Sink - 12/3/2025

The Dallas Cowboys (6-5) are en route to Ford Field on Thursday where they will take on the Detroit Lions (7-5). Detroit opens this matchup as 3-point favorites from Vegas oddsmakers. The total has been set at 54.5. This matchup report includes NFL odds, predictions, and a free pick against the spread. Read More >>

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Green Bay Packers vs Detroit Lions Prediction, 11/27/2025 NFL Picks, Best Bets & Odds Week 13
by Tony Sink - 11/25/2025

The Green Bay Packers (7-3) are traveling to Ford Field on Thursday where they will go up against the Detroit Lions (7-4). Green Bay is 2.5-point dogs. The total comes in at 49. This matchup report includes NFL odds, predictions, and a free pick against the spread. Read More >>

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New York Giants vs Detroit Lions Prediction, 11/23/2025 NFL Picks, Best Bets & Odds Week 12
by Parlays Pundit - 11/19/2025

Ford Field is the location where the Detroit Lions (6-4) will attempt to beat the New York Giants (2-9) on Sunday. Detroit opens this game as 10.5-point favorites from oddsmakers. The betting total is set at 50.5. We have included an expert NFL pick and parlay for todays game against the spread. Read More >>

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Detroit Lions vs Philadelphia Eagles Prediction, 11/16/2025 NFL Picks, Best Bets & Odds Week 11
by Guy Bruhn - 11/12/2025

Lincoln Financial Field is the site where the Philadelphia Eagles (7-2) will play the Detroit Lions (6-3) on Sunday. Detroit is 1.5-point dogs from oddsmakers. The total is set at 49. This matchup report includes betting lines and our NFL pick of the day for this game. Read More >>

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Detroit Lions vs Washington Commanders Prediction, 11/9/2025 NFL Picks, Best Bets & Odds Week 10
by Josh Schonwald - 11/5/2025

The Detroit Lions (5-3) are en route to Northwest Stadium on Sunday where they will attempt to defeat the Washington Commanders (3-6). Washington opens this contest as 9.5-point dogs from Vegas oddsmakers. The total has been set at 49.5. This matchup report includes odds, NFL betting predictions and a free pick against the spread. Read More >>

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Minnesota Vikings vs Detroit Lions Prediction, 11/2/2025 NFL Picks, Best Bets & Odds Week 9
by Josh Schonwald - 10/28/2025

The Minnesota Vikings (3-4) are traveling to Ford Field on Sunday where they will go up against the Detroit Lions (5-2). Minnesota opens as 8.5-point dogs from Vegas oddsmakers. The over-under has been set at 47.5. This matchup report includes football betting lines and our pick of the day for this game. Read More >>

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Tampa Bay Buccaneers vs Detroit Lions Prediction, 10/20/2025 NFL Picks, Best Bets & Odds Week 7
by Guy Bruhn - 10/14/2025

The Detroit Lions (4-2) will try to defeat the Tampa Bay Buccaneers (5-1) at Ford Field on Monday. Tampa Bay opens this contest as 4.5-point dogs. The over-under is 53. This matchup report includes betting lines and our NFL pick of the day for this game. Read More >>

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Detroit Lions vs Kansas City Chiefs Prediction, 10/12/2025 NFL Picks, Best Bets & Odds Week 6
by Tony Sink - 10/7/2025

GEHA Field at Arrowhead Stadium is the location where the Kansas City Chiefs (2-3) will play the Detroit Lions (4-1) on Sunday. Kansas City is 1-point underdogs from oddsmakers. The over-under has been set at 50.5. This report includes betting odds and our expert football picks for todays game. Read More >>

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Detroit Lions vs Cincinnati Bengals Prediction, 10/5/2025 NFL Picks, Best Bets & Odds Week 5
by Guy Bruhn - 9/30/2025

The Detroit Lions (3-1) are on their way to Paycor Stadium on Sunday where they will compete against the Cincinnati Bengals (2-2). Cincinnati opens this contest as 10-point dogs from Vegas oddsmakers. The total is set at 49. This matchup report includes Vegas odds and a free NFL pick for tonight. Read More >>

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Cleveland Browns vs Detroit Lions Prediction, 9/28/2025 NFL Picks, Best Bets & Odds Week 4
by Guy Bruhn - 9/23/2025

Ford Field is where the Detroit Lions (2-1) will attempt to defeat the Cleveland Browns (1-2) on Sunday. Detroit is 9.5-point favorites. The total has been set at 45.5. This matchup report includes Vegas odds and a free NFL prediction for tonight. Read More >>

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Detroit Lions vs Baltimore Ravens Prediction, 9/22/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025

The Detroit Lions (1-1) are on their way to M&T Bank Stadium on Monday where they will try to defeat the Baltimore Ravens (1-1). Baltimore is 5.5-point favorites. The total comes in at 51.5. This matchup report includes odds, betting predictions and a free pick against the spread. Read More >>

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Chicago Bears vs Detroit Lions Prediction, 9/14/2025 NFL Picks, Best Bets & Odds Week 2
by Parlays Pundit - 9/9/2025

The Detroit Lions (0-1) are welcoming the Chicago Bears (0-1) at Ford Field on Sunday. Chicago opens this game as 6-point underdogs from Vegas oddsmakers. The over-under is 47.5. We have included an expert NFL pick and parlay for todays game against the spread. Read More >>

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Detroit Lions vs Green Bay Packers Prediction, 9/7/2025 NFL Picks, Best Bets & Odds Week 1
by Tony Sink - 9/3/2025

Lambeau Field is the site where the Green Bay Packers (11-6 last year) will meet the Detroit Lions (15-2 last season) on Sunday. Green Bay is 2.5-point favorites from oddsmakers. The total is 47.5. This report includes betting odds and our expert football picks for todays game. Read More >>

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Washington Commanders vs Detroit Lions Prediction, 1/18/2025 NFL Picks, Best Bets & Odds Divisional Playoffs
by Guy Bruhn - 1/13/2025

Ford Field is the site where the Detroit Lions (15-2) will play the Washington Commanders (12-5) on Saturday. Washington opens this contest as 9.5-point underdogs. The over-under has been set at 55. This report includes betting predictions and our expert NFL picks for todays game. Read More >>

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Minnesota Vikings vs Detroit Lions Prediction, 1/5/2025 NFL Picks, Best Bets & Odds Week 18
by Josh Schonwald - 12/31/2024

The Detroit Lions (13-2) are welcoming the Minnesota Vikings (14-2) at Ford Field on Sunday. Detroit opens as 2.5-point favorites. The betting total comes in at 52. This games report has current odds, betting predictions, and free picks against the spread. Read More >>

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Detroit Lions vs San Francisco 49ers Prediction, 12/30/2024 NFL Picks, Best Bets & Odds Week 14
by Tony Sink - 12/23/2024

The San Francisco 49ers (6-9) will take on the Detroit Lions (13-2) at Levi's Stadium on Monday. Detroit opens this game as 3.5-point favorites. The total is set at 51. This matchup report includes odds, betting predictions and a free pick against the spread. Read More >>

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