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2025 Arizona Cardinals Season Win Total Picks

by Robert Ferringo - 8/8/2025

Arizona Cardinals season win total picks Kyler Murray

The third year has been the charm for Arizona Cardinals head coaches.

Ken Whisenhunt increased Arizona’s win total each of his first three years, including a high-water mark of 10 wins in his third attempt. Bruce Arians did the same thing, increasing Arizona’s win total each of his first two years and then hitting a high of 13 wins in his third frame.

Even failure Kliff Kingsbury kept to the script, increasing Arizona’s win total each of his first three seasons, including a 11-win campaign in Year 3 at the helm.

It is now Jonathan Gannon’s third year leading the Cardinals. Gannon matched Kingsbury’s four wins in 2021 in his first year. He increased his win total to eight last season.

So now is Arizona poised for another Year 3 breakout?

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ARIZONA CARDINALS 2025 OFFENSE

This season may be a defining moment in Kyler Murray’s disappointing career. The malcontent little sprite has been a starting quarterback in the NFL for six years. He’s posted a winning record exactly once. Murray is 36-45-1 with one playoff appearance in his career and is 14-22 with three straight losing seasons since the start of 2022.

It’s time for Murray to prove that he is not a loser.

Some guys that are definitely not losers: running back James Conner, tight end Trey McBride, and wide receiver Marvin Harrison Jr.

Much like Caleb Williams in Chicago, Harrison was unfairly considered a “disappointment” in his rookie season. Harrison managed 62 catches for 885 yards and eight touchdowns. Those are solid numbers for anyone, but especially for a first-year player. Don’t be surprised if he surpasses all of them this fall.

Arizona was No. 11 in total offense and No. 7 in rushing. Connor and Murray combined for over 1,600 rushing yards and helped establish the Cardinals as the No. 8 most efficient third down offense in the league.

The Cards have a very good starting five across the offensive line. But they lack depth. And they desperately need a third option – beyond Harrison and McBride – to emerge in the passing game.

ARIZONA CARDINALS 2025 SCHEDULE

Sun, Sep 7        @ New Orleans Saints             1:00 p.m.

Sun, Sep 14     vs Carolina Panthers               4:05 p.m.

Sun, Sep 21     @ San Francisco 49ers           4:25 p.m.

Thu, Sep 25     vs Seattle Seahawks                8:15 p.m.

Sun, Oct 5        vs Tennessee Titans                4:05 p.m.

Sun, Oct 12      @ Indianapolis Colts               1:00 p.m.

Sun, Oct 19      vs Green Bay Packers              4:25 p.m.

Week 8             BYE

Mon, Nov 3      @ Dallas Cowboys                    8:15 p.m.

Sun, Nov 9       @ Seattle Seahawks                4:05 p.m.

Sun, Nov 16     vs San Francisco 49ers           4:05 p.m.

Sun, Nov 23     vs Jacksonville Jaguars           4:05 p.m.

Sun, Nov 30     @ Tampa Bay Buccaneers    1:00 p.m.

Sun, Dec 7        vs Los Angeles Rams               4:25 p.m.

Sun, Dec 14     @ Houston Texans                   1:00 p.m.

Sun, Dec 21     vs Atlanta Falcons                    4:05 p.m.

Sun, Dec. 28    vs Cincinnati Bengals              TBD

Week 18           @ Los Angeles Rams               TBD

ARIZONA CARDINALS 2025 SEASON PICKS AND PREDICTIONS

The Cardinals have underachieved, relative to their Pythagorean win expectation, by a full game in each of Gannon’s two years at the helm. Is that on Gannon? Is it on Murray? Is it a statistical fluke due for a correction?

We will find out. But it is tough to trust a Cardinals franchise that is just 3-6 against their Las Vegas season win total over the last nine seasons.

One reason why I do find it a little easier to buy in to Arizona this season is a significantly weaker schedule. Crossing over against the NFC and AFC South divisions – the two weakest in the league – is a major coup for the Cards.

Arizona only has one back-to-back road trip and it comes after a bye week. They also only have one short week disadvantage and despite several trips east, the Cardinals only have four 10 a.m. PST kickoffs.

I think that Gannon can follow his predecessors and manufacture that third-year bump. It is a now-or-never moment for Murray and this franchise. And while I am skeptical of Murray as a leader and overall player, I think there is enough around him that even he can’t screw up what should be a season where the Cards threaten 10 wins and a return trip to the playoffs.

Robert Ferringo has posted seven of 10 winning football seasons, including last year thanks to an astounding +10,830 three-month run. Robert banked nearly +40,000 in profit between 2010-2019 for a 10-year average profit of nearly +4,000. He has earned 11 of 16 overall winning years and 69 of 114 winning months while also going 23-9 with his football futures rated 5.0+ and earning 16 of 19 winning Super Bowls. He is a member of the Football Writers Association of America and he is set for another amazing football season. SIGN UP HERE TODAY AND TAKE ADVANTAGE OF OUR 3-FOR-1 FOOTBALL SPECIALS!

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