NFL Office Pool Picks Week 10 - ATS Predictions for Every Game!

One of the most difficult tasks in the world of sports betting is coming out on top of your season-long against the spread office pool. There are 272 regular season games each year, and anything higher than a 50% record is quite impressive. Last week, we had a negative showing with a 5-9 record against the spread, but we are as hungry as ever to get back in the green this week. It has been a season for the favorites this year, but the dogs were barking in Week 9 as the favorites went just 8-6 straight up and 6-8 against the spread. Fourteen teams are in action this week, so let’s dive right into the against the spread picks for Week 10.
Doc’s Sports offers NFL expert picks for every game on our NFL predictions page.
Las Vegas Raiders (+9.5) Over Denver Broncos
The Raiders haven’t been playing inspiring football this year, and they just traded away their leading receiver, Jakobi Meyers. However, that doesn’t mean they should be massive underdogs in this divisional matchup. Denver’s offense is incredibly inconsistent, and expecting a double-digit win is too much to ask for. The Broncos will keep their win streak alive, but it will be their fifth one-possession win in the last six games. Broncos 24, Raiders 17
Indianapolis Colts (-6.5) Over Atlanta Falcons
As long as the Colts don’t turn the ball over six times, this is their game to lose. The Falcons don’t have the same dominant pass rush that the Steelers had last week, and I struggle to see them slowing down Daniel Jones and the Colts' offense. The Falcons are crumbling, and a road game against an angry Colts side is a recipe for disaster. Colts 35, Falcons 20
Jacksonville Jaguars (+1.5) Over Houston Texans
CJ Stroud is still in concussion protocol, and even a healthy Stroud doesn’t make the Texans favorites in this one. The Houston offensive line is dreadful, and an invigorated Jaguars side will be able to pull off this small upset. Jacksonville showed its hand at the deadline that it believes this is its year, and it all starts with a victory in Houston. If Stroud is out, the Jags will win by double digits, but even if he is in, this is still a great pick to make. Jaguars 33, Texans 13
Chicago Bears (-3.5) Over New York Giants
The Bears needed a miracle last week to beat the Bengals, but that was after Cincinnati had a late onside kick miracle of their own. Chicago is better on both sides of the ball compared to the Giants, who are simply looking to play out the season and regroup for next year. The Bears have choked in the past, but Ben Johnson’s elite offense, led by Caleb Williams, will put up 30+ against New York. Will the Giants be able to keep pace? I doubt it. Bears 38, Giants 17
Baltimore Ravens (-4.5) Over Minnesota Vikings
Both of these teams got crucial wins last week, but it will be the Ravens that maintain their momentum in this matchup. Baltimore has extra rest, having played on Thursday, and a healthy Lamar Jackson has transformed the outlook of this team. Their strong ground attack will take advantage of a struggling Vikings run defense, and JJ McCarthy will fall short of another miraculous comeback. Ravens 27, Vikings 21
New York Jets (+2.5) Over Cleveland Browns
The Jets traded away Sauce Gardner and Quinnen Williams at the deadline, which has inflated their line as home underdogs. There isn’t a team in the league that the lowly Browns deserve to be road favorites against, as they have lost 12 road games in a row, with the last 9 coming by multiple possessions. It’s an ugly pick, but the Jets have a lot of value with this kind of line. Jets 20, Browns 17
Carolina Panthers (-5.5) Over New Orleans Saints
The Panthers have done a spectacular job at running the football, and they will obliterate a free-falling Saints run defense. Carolina is 5-4 with a 3-1 home record, and there is no reason to start doubting them now. New Orleans traded away their only playmaker at the trade deadline, and there is truly no hope for this sorry franchise. Maybe the Saints get a backdoor cover, but more often than not, the Panthers hold them out of the endzone with 40+ minutes of possession time. Panthers 17, Saints 6
Miami Dolphins (+9.5) Over Buffalo Bills
One of these teams is coming off an embarrassing primetime loss, while the other just took down the Chiefs. Despite that, we will still side with Miami and this massive spread. The Dolphins' offense has been surprisingly effective this season, and even against the Ravens last week, they still moved the ball well. Buffalo has dominated the Dolphins with 14 wins in the last 15, but Miami can usually keep it respectable at home. Bills 27, Dolphins 20
New England Patriots (+2.5) Over Tampa Bay Buccaneers
What have we seen from New England that makes them an underdog in this matchup? They have won six straight with MVP-caliber play from Drake Maye, and deserve to be favorites against the Buccaneers. The injuries have piled up for Tampa Bay, and even a bye week won’t let them get their stars back on the field. The Patriots' passing attack is too good to overlook. Patriots 27, Buccaneers 24
Arizona Cardinals (+6.5) Over Seattle Seahawks
The Cardinals are criminally underrated in this matchup, as this is a game they could win outright. They have a positive point differential despite being 3-5 on the season, and look confident with Jacoby Brissett in the pocket. This is a prime letdown spot for the Seahawks after a big primetime win against the struggling Commanders, and there is no justification for this massive spread in a divisional matchup. Arizona will tighten up the NFC West race with a shocking upset win. Cardinals 25, Seahawks 24
Los Angeles Rams (-3.5) Over San Francisco 49ers
A battle of California has high stakes in the NFC West race, but the Rams shouldn’t have too many problems picking up this win. Matthew Stafford is playing the best football of his career, as the Rams have a league-high 258 passing yards per game. The 49ers' pass defense isn’t what it once was, and the Rams shouldn’t have a problem slicing up the 49ers for a late victory. Rams 28, 49ers 21
Detroit Lions (-8.5) Over Washington Commanders
The Lions will get revenge for their playoff loss from last season, taking advantage of a growing injury list for the Commanders. Washington is missing too many key pieces on both sides of the ball to keep this one close. Jayden Daniels won’t play; their offense is uninspiring, and their defense has allowed 36.6 PPG in the last three games. All three of those matchups were 20+ point losses, and another big defeat is on the cards in this one. Lions 45, Commanders 17
Pittsburgh Steelers (+3) Over Los Angeles Chargers
We can’t always expect six takeaways from the Steelers defense, but the highest-paid unit in the league showed what they are capable of. Joe Alt going down for the season hurts Justin Herbert’s blindside protection, and that is after Rashawn Slater also went down with an injury. No protection for Herbert will allow the Steelers defense to feast once again, and Aaron Rodgers will take care of the rest on the other side of the ball. Steelers 17, Chargers 13
Philadelphia Eagles (+2.5) Over Green Bay Packers
The Eagles haven’t looked pretty, but they keep finding ways to eke out victories this season. Their physicality is hard to contain, and they had an extra-long bye week for this Monday Night affair. Green Bay has been too inconsistent on offense to trust against legitimate Super Bowl contenders. Eagles 27, Packers 17
Season Record: 60-75
Last Season Record: 142-125-5
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