NFL Office Pool Picks Week 6 - ATS Predictions for Every Game!

There isn’t a tougher task in sports than winning a season-long office pool. All year long, Doc’s Sports will be providing free against-the-spread picks for all 272 NFL games. We went 142-125-5 last season against the spread, and clawed our way back to 32-32 this year after a disastrous Week 1. Last week, we went 7-7 against the spread to hover at .500 with a 39-39 record on the season. Around the league, the upsets were brewing as the favorites went just 6-9 straight up and against the spread. This was the first week of the season that favorites fell short, and it is a good reminder that anything is possible on any given week in the NFL. The Week 6 lines are out, and it’s time to get into your NFL picks against the spread for all 15 matchups.
Doc’s Sports offers NFL expert picks for every game on our NFL predictions page.
New York Giants (+7.5) Over Philadelphia Eagles
It takes a lot for us to fade a home underdog in a divisional matchup, and we certainly won’t be breaking our rule with the Giants this week. New York turned the ball over five times last week, but they actually played well outside of those disastrous plays. The Eagles look beatable as their offensive line gets hit with injuries, and this line is above crucial 6 and 7-point win margins. This could backfire, but more often than not, the Giants hang around. Eagles 20, Giants 17
Denver Broncos (-7) Over New York Jets
This one goes down in London early Sunday morning, and the Broncos shouldn’t have any problems shaking jet lag for a comfortable victory. New York is the only winless team left this season, as they have seriously struggled on defense. Bo Nix is due for an offensive explosion, and the Jets are a prime victim. Justin Fields has been playing well on offense, but a lack of defensive support means the Broncos win by double digits. Broncos 35, Jets 20
Pittsburgh Steelers (-5.5) Over Cleveland Browns
Laying a chunky spread with the Steelers is never fun, given their gritty style of play. However, they are significantly better than Cleveland on both sides of the ball. Joe Flacco’s leadership is out of the equation for the Browns, leaving Dillon Gabriel and Shedeur Sanders as the only two quarterbacks. Pittsburgh is coming off its bye, is fully rested, and is at home. It won’t be a blowout, but the Steelers grind out a win by a touchdown. Steelers 20, Browns 13
Los Angeles Chargers (-4) Over Miami Dolphins
The Chargers were unlucky to lose by 17 to Washington as a few key penalties and special team plays cost them victory. They will be able to get right back on track against Miami, who blew a 17-point lead to the Panthers last week. Miami has still been able to score without Tyreek Hill, but its defense has been the real concern. Justin Herbert will pick them apart and score 30+ points more often than not. Will the Dolphins be able to keep pace? Unlikely. Chargers 33, Dolphins 24
New England Patriots (-3.5) Over New Orleans Saints
Both of these teams are coming off feel-good Week 5 wins, but don’t get confused. The Saints are still tanking for a quarterback, while the Patriots have legitimate playoff hopes. Drake Maye is playing some of the best football of his life right now, and the Saints' defense will not slow him down. It’s a bit surprising to see a short spread between these two, and we will happily lay the points with the Pats. Patriots 24, Saints 10
Jacksonville Jaguars (-1) Over Seattle Seahawks
The Jaguars pulled off a stunning upset on Monday Night Football to move to 4-1 on the season. They are at home with a short spread, and we can’t trust Seattle to pull off the small upset. Trevor Lawrence is spreading the ball nicely on offense and will really challenge the Seahawks' secondary. This is a great matchup that could go either way, but we have to side with the hotter team at home with a minimal spread. Jaguars 24, Seahawks 21
Indianapolis Colts (-6.5) Over Arizona Cardinals
We have jumped on the Colts bandwagon and will not be getting off until they slow down. Daniel Jones is an MVP candidate through five weeks, and the Colts could be 5-0 if it weren’t for an uncontested end zone drop. Speaking of those, the Cardinals are more than familiar with that feeling after Emari Demercano blew it against the Titans last week. All three of the Cardinals' losses have been on last-second field goals, but they have been playing much worse than those scorelines suggest. The Colts keep rolling with another big win. Colts 35, Cardinals 24
Los Angeles Rams (-7.5) Over Baltimore Ravens
Lamar Jackson is unlikely to play in this one, and we can’t trust Cooper Rush to keep things close. The Rams are a legitimate Super Bowl contender and will see this as an easy win in Baltimore. The Ravens' defense has collapsed, their run game is broken, and major changes could be coming soon. It’s a spread that is a few points wider than I’d like, but the Rams are still the way to go. Rams 30, Ravens 17
Dallas Cowboys (-3) Over Carolina Panthers
The Cowboys' offense is among the best in the league, and will almost certainly drop 30+ points against the Panthers. They have scored 37 or more points in three games this season, and the Panthers' defense is far from a stellar unit. Dallas’ defense is still suspect, but their offense is usually able to outscore their lapses. Carolina still has lots to prove on both sides of the ball, and a comeback win over the struggling Dolphins isn’t enough for us to buy into them just yet. Cowboys 35, Panthers 20
Tennessee Titans (+5.5) Over Las Vegas Raiders
This is an ugly matchup, but one where the pick is easy. Las Vegas has dropped four straight games, and they frankly haven’t even been competitive. Tennessee is coming off its first win of the season, and while it was in dramatic fashion, the Titans will still be uplifted heading into this matchup. Laying nearly a touchdown with the Raiders isn’t an option against anyone in the league, and it wouldn’t be surprising to see the Titans win this one outright. Titans 20, Raiders 13
Tampa Bay Buccaneers (-3) Over San Francisco 49ers
The 49ers pulled off a miracle on Thursday night, but that doesn’t mean they can compete with a team like Tampa Bay. Baker Mayfield continues to dominate late in the fourth quarter, and this is not a team I want to fade if the game is tight in the closing stages. The Buccaneers are humming on both sides of the ball, while the 49ers are still incredibly banged up. Buccaneers 27, 49ers 21
Green Bay Packers (-14) Over Cincinnati Bengals
Joe Flacco’s arrival boosts the stock of the Bengals, but they are coming up against the Packers at the wrong time. Green Bay will have had its bye week to boil over its tie against the Cowboys, and will take out its frustration against the Bengals. Flacco can’t help the Bengals' defense, and this one will turn into a blowout quickly. Packers 41, Bengals 17
Detroit Lions (+2.5) Over Kansas City Chiefs
The Chiefs will be desperate for a win at 2-3, but we have to take the points where we can get them in this matchup. Kansas City’s defense is no longer the dominant unit it once was. Detroit will find success on the offensive side of the ball and will go shot-for-shot with Mahomes and the Kansas City offense. This short spread may not feel like much, but when two behemoths face off who are both desperate to win, every point counts. The Chiefs win on a last-second field goal, but the Lions get the cover. Chiefs 25, Lions 24
Buffalo Bills (-4.5) Over Atlanta Falcons
The Falcons have a rest advantage as well as the benefit of playing at home, but we are still unable to fade the Bills. Buffalo lost their first game of the season last week, and will not lose two in a row against the Falcons. Atlanta has been too inconsistent to trust against Super Bowl contenders this season. Bills 31, Falcons 17
Washington Commanders (-4.5) Over Chicago Bears
Jayden Daniels was thrust back into the lineup last week and looked as good as ever. Washington’s run game has really started to thrive, and that has allowed Daniels to get favorable coverages when it is time to throw the ball downfield. The Bears are coming off a bye, which is always scary to fade, but we will keep riding these short spreads with the Commanders at home until something changes. Commanders 27, Bears 21
Season Record: 39-39
Last Season Record: 142-125-5
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