NFL Picks: Parlays, Best Bets, Player Props, and Expert Predictions Against the Spread.
This Weeks NFL expert picks and best NFL bets as well as parlays and player props. All of our NFL predictions are against the spread. Bookmark this page as it will be updated daily.
Thursday Night Football Picks: Miami Dolphins vs Buffalo Bills
by Mike Allen - 9/16/2025
The first two weeks of the 2025 NFL regular season have been quite interesting. There haven't been many surprises yet, other than the extent to which some teams can struggle. On Thursday Night Football this week, the mopey, dopey Miami Dolphins make their way up to Orchard Park, New York, in an "attempt" to take one from the AFC East-leading Bills.
Cincinnati Bengals vs Minnesota Vikings Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Parlays Pundit - 9/16/2025
U.S. Bank Stadium is the location where the Minnesota Vikings (1-1) will attempt to beat the Cincinnati Bengals (2-0) on Sunday. Cincinnati opens this contest as 3-point underdogs. The total is 42. We have included an expert NFL pick and parlay for todays game against the spread.
Green Bay Packers vs Cleveland Browns Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Guy Bruhn - 9/16/2025
Huntington Bank Field is the place where the Cleveland Browns (0-2) will try to beat the Green Bay Packers (2-0) on Sunday. Green Bay opens this matchup as 8-point favorites from Vegas oddsmakers. The total comes in at 42. This report includes betting predictions and our expert NFL picks for todays game.
New York Jets vs Tampa Bay Buccaneers Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025
Raymond James Stadium is the location where the Tampa Bay Buccaneers (2-0) will try to beat the New York Jets (0-2) on Sunday. Tampa Bay opens this game as 7-point favorites from oddsmakers. The total comes in at 45.5. This matchup report has Vegas lines and an expert NFL football pick for your daily winner.
Detroit Lions vs Baltimore Ravens Prediction, 9/22/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025
The Detroit Lions (1-1) are on their way to M&T Bank Stadium on Monday where they will try to defeat the Baltimore Ravens (1-1). Baltimore is 5.5-point favorites. The total comes in at 51.5. This matchup report includes odds, betting predictions and a free pick against the spread.
Los Angeles Rams vs Philadelphia Eagles Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Josh Schonwald - 9/16/2025
The Los Angeles Rams (2-0) are en route to Lincoln Financial Field on Sunday where they will meet the Philadelphia Eagles (2-0). Philadelphia opens this contest as 3.5-point favorites from Vegas oddsmakers. The betting total is set at 44.5. This games report has current odds, betting predictions, and free picks against the spread.
Pittsburgh Steelers vs New England Patriots Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Guy Bruhn - 9/16/2025
The New England Patriots (1-1) will play the Pittsburgh Steelers (1-1) at Gillette Stadium on Sunday. New England opens this game as 1-point dogs from Vegas oddsmakers. The total is set at 44.5. This matchup report includes Vegas odds and a free NFL prediction for tonight.
Arizona Cardinals vs San Francisco 49ers Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Guy Bruhn - 9/16/2025
Levi's Stadium is the place where the San Francisco 49ers (2-0) will attempt to beat the Arizona Cardinals (2-0) on Sunday. Arizona opens this game as 1.5-point underdogs from oddsmakers. The total is set at 43.5. This matchup report includes betting lines and our NFL pick of the day for this game.
Denver Broncos vs Los Angeles Chargers Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Guy Bruhn - 9/16/2025
SoFi Stadium is the location where the Los Angeles Chargers (2-0) will try to beat the Denver Broncos (1-1) on Sunday. Los Angeles opens this game as 2.5-point favorites from Vegas oddsmakers. The total is 46. This matchup report includes Vegas odds and a free NFL pick for tonight.
Kansas City Chiefs vs New York Giants Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Josh Schonwald - 9/16/2025
The Kansas City Chiefs (0-2) are headed to MetLife Stadium on Sunday where they will attempt to defeat the New York Giants (0-2). Kansas City opens this matchup as 5.5-point favorites from oddsmakers. The total has been set at 45.5. This matchup report includes Vegas odds and a free NFL pick for tonight.
Dallas Cowboys vs Chicago Bears Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025
The Dallas Cowboys (1-1) are headed to Soldier Field on Sunday where they will compete against the Chicago Bears (0-2). Chicago is 1-point underdogs. The total comes in at 50. This report includes betting odds and our expert football picks for todays game.
Las Vegas Raiders vs Washington Commanders Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Guy Bruhn - 9/16/2025
The Washington Commanders (1-1) will play the Las Vegas Raiders (1-1) at Northwest Stadium on Sunday. Las Vegas is 3.5-point dogs from Vegas oddsmakers. The betting total comes in at 44.5. This matchup report has your NFL football pick of the day as well as NFL football odds for the game.
New Orleans Saints vs Seattle Seahawks Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Josh Schonwald - 9/16/2025
The New Orleans Saints (0-2) are on their way to Lumen Field on Sunday where they will try to defeat the Seattle Seahawks (1-1). Seattle opens this matchup as 7.5-point favorites from Vegas oddsmakers. The total is 41.5. This matchup report includes odds, NFL betting predictions and a free pick against the spread.
Atlanta Falcons vs Carolina Panthers Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Josh Schonwald - 9/16/2025
The Carolina Panthers (0-2) will compete against the Atlanta Falcons (1-1) at Bank of America Stadium on Sunday. Atlanta opens this contest as 5-point favorites from Vegas oddsmakers. The total comes in at 43.5. This report has odds and your NFL football predictions for todays game against the spread.
Indianapolis Colts vs Tennessee Titans Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Josh Schonwald - 9/16/2025
Nissan Stadium is the place where the Tennessee Titans (0-2) will try to beat the Indianapolis Colts (2-0) on Sunday. Indianapolis opens as 3.5-point favorites. The total comes in at 43.5. This matchup report includes football betting lines and our pick of the day for this game.
Miami Dolphins vs Buffalo Bills Prediction, 9/18/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025
The Buffalo Bills (2-0) welcome the Miami Dolphins (0-2) at Highmark Stadium on Thursday. Miami opens this matchup as 12.5-point underdogs from Vegas oddsmakers. The total is 49.5. This matchup report includes NFL odds, predictions, and a free pick against the spread.
Houston Texans vs Jacksonville Jaguars Prediction, 9/21/2025 NFL Picks, Best Bets & Odds Week 3
by Tony Sink - 9/16/2025
The Houston Texans (0-2) are en route to EverBank Stadium on Sunday where they will meet the Jacksonville Jaguars (1-1). Jacksonville opens this contest as 1-point favorites from Vegas oddsmakers. The total comes in at 44.5. This game report has an NFL football pick, betting odds, and predictions for tonights key matchup.
Monday Night Football Picks: Los Angeles Chargers vs Las Vegas Raiders
by Mike Allen - 9/11/2025
We have not one but two games this Monday night. We had our pick, if you will, for which game to predict. I chose the AFC West matchup between the visiting Chargers and the home Las Vegas Raiders over the Buccaneers at Texans game because we more or less know what we're getting with a divisional game than one like the latter, where we have two organizations that've met just six times in the past 23 years.
Sunday Night Football Picks: Atlanta Falcons at Minnesota Vikings
by Mike Allen - 9/11/2025
I hope everyone survived a wild Week 1. I had the Atlanta Falcons (+2.5) at home on Sunday. It looked like we were gonna at least make it to overtime, but no. Younghoe Koo came up to the plate in the bottom of the ninth with a chance to tie the Bucs. It was only a 44-yarder, and the ball sailed wide to the right.
Thursday Night Football Picks: Green Bay Packers vs Washington Commanders
by Mike Allen - 9/9/2025
Guys, I’m still taking my time digesting Week 1. How much fun was that? We got to see the Dallas Cowboys compete with the Philadelphia Eagles without Micah Parsons, who, on Sunday, looked like the best defender in the NFL. We picked the Ravens and said it would have to be another turnover(s) for them to lose, and that's what happened.
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Please note that the NFL picks above for tonight's games are not computer based. All of these articles are written by our talented staff.
Free NFL Picks
You've waited long enough for the NFL to return, and now it's time to start turning a profit off of the most popular and highest volume of wagering sport there is in North America. Football is king when it comes to being able to consistently handicap on a weekly basis, and there are a ton of angles to capitalize on. Doc's NFL experts are second to none when it comes to turning a profit on the gridiron, and you can join them in winning with the release of their weekly free picks on every single NFL game from Week 1 to the Super Bowl in February.NFL Expert Picks and Predictions
Here are Doc's Sports, you will find all the free picks you can handle, which include but are not limited to NHL, MLB, NBA, College Football, and of course, the NFL picks. We utilize our social media platforms to ensure free picks are readily available for those who are looking for opinion and insight on some of the most popular games on the betting board as well as those that are likely to not garner much attention. We have an NFL video page that is updated weekly with tidbits and NFL free picks on key games of the week. If you're looking for even more than free picks and insight, be sure to capitalize on our complimentary $60 in premium member selections that can be used for any handicapper in any sport. You can get started with that by clicking the join button at the top of the page.Get your NFL Picks Today, and Every Day!
Because the NFL schedule is different than your typical daily NHL, MLB or NBA handicapping, we release our free picks and write-ups for each game on Tuesday, following Monday Night Football. These picks are released with opening line odds and as such, the lines are subject to change as kickoff approaches on Sunday. At Doc's, we take this into account when releasing free plays and advised on how high you should play a line to or when to avoid the game that sees major line movement. It's imperative that you understand that betting on the NFL is not always about betting the right teams, it's about betting the right number as well.NFL Picks Against the Spread
There is something glorious about being able to consistently win while betting games against the spread. In the NFL, betting teams against the spread or ATS is the most popular way to bet on football games. A spread is a sportsbook's way of leveling the playing field when two teams hook up and one team is noticeably better than the other one. For each game played, you would see a line that looks like this: New England -7 over New York Jets. That means that the sportsbooks think the Patriots are seven points better than the Jets and as such should win by seven or more points. If Doc's handicapper agrees with the books, they would lay the seven points and take New England Against the Spread. (ATS) If they don't, they would take the Jets Against the Spread (ATS) and have a seven-point cushion with regards to the final score. At Doc's, the majority of our free picks and members selections are against the spreads. There is sometimes value with taking an underdog on the money line, and there are certainly great spots to bet the total.NFL Over/Under Picks
In today's NFL, the style of play and systems used generally trend towards the over as most teams want to play fast and utilize their team speed and weapons on offense. Defenses are often overlooked, and as such most bettors or casual fans want to see points and more points. While there are great spots to bet NFL games to over the total, there are even more spots to grab an under on an inflated line. For example, if two teams are hooking up and they've put up a ton of points in their last game, sportsbooks will inflate the line knowing the public will think that the 'over' is the play based on recent play. However, an inflated line leaves bettors with a great chance to cash on the under as both of those teams will likely want to shore up the defense and play a sound football game. Doc's handicappers are some of the best in the industry at finding those inflated lines and hitting contrarian plays on NFL totals. Along with NFL ATS free picks, we offer predictions on totals that are insightful and stat-packed with good tidbits to help you understand what the right side of the total should be.NFL Parlay Picks
If you asked five people in a room their thoughts on parlays, you would likely get five different answers. Parlays, while a long-term losing prospect, can provide value when used in the right way. NFL Parlay picks offer a bettor a small-risk, high-reward type wager that can be very profitable when given the right information to process. Typically speaking, an NFL parlay pick would consist of two or more selections on different games. Nowadays, the big thing in the betting industry is the Same Game Parlays that are offered at a select number of sportsbooks. These same-game parlays offer up a way for a bettor to focus on one game and parlay a host of selections together for a massive payday. For example, if you think a football game is going to be high scoring, you might parlay the total, a few touchdown scorers and the point spread result together. If the game is high-scoring, chances are the players you selected got a touchdown and you would be very likely to win your bet. At Doc's Sports, we offer parlays when the situation calls for it. They are rare, but when we see an opportunity to show a great return, we simply do not pass it up.NFL Playoff Predictions
The NFL playoffs are unlike any other North American playoffs. They are one-game, single-elimination style games with the better seed hosting the lower seed. Time and time again, we've seen the lower seed (the road team) escaping the Wild Card Game with a win because they are the better team and played in a tougher division. Sometimes, betting on the NFL playoffs is not about picking the better team, it's about picking the team that is hot and confident heading into the matchup. It's also imperative to get the best number possible no matter which side you like in the game. Lines very rarely change drastically throughout the days leading up to kickoff, but a half-point could make the difference between winning and losing your wager. Shop around and bet the team you like at the right time while getting the best line. If you have any questions or ideas for this section, please email service@docsports.com Best of Luck!
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